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SeqOnce Biosciences isn't accepting new investments

SeqOnce Biosciences’ deadline was May 1, 2025

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SeqOnce Biosciences

SeqOnce bringing a wrecking ball to upend, disrupt and revolutionize the $34 billion genomics market
B2B Healthcare Facilities & Equipment Healthtech D2C Biotechnology
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Featured image of SeqOnce Biosciences
$117,316
Raised
67
Investors
Successfully funded and closed on May 1, 2025.
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Closed on May 1, 2025. Information may not be up-to-date. Campaign closed on May 1, 2025. Information displayed may not be up-to-date.
Opportunity Product Traction Biz. model Vision and strategy Leadership
About Team

Documents

Republic (OpenDeal Portal LLC, CRD #283874) is hosting this Reg CF securities offering by SeqOnce Biosciences Inc. View the official SEC filing and all updates:
Official SEC Logo Form C SEC.gov
Company documents
SeqOnce Biosciences SAFE SeqOnce - Form C .pdf
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Hear from some of the 67 investors in SeqOnce Biosciences


Show more

Highlights


  • Generated over $45M revenue to date - Run rate of $100K to $250K/month
  • New Game-Changing Technology: Creating massive future valuation potential
  • Launched 9 products, Developed 2 new novel technologies
  • Diversified: Products and Markets - Including DTC (Direct to Consumer)
  • Patent protected: Patent coverage across the US, EU, and China
  • Minimal outside investment: Less than $1M raised total, clean cap table
  • Investors include: Wavemaker 360 Health, a top-tier venture capital firm

Opportunity


The Company

SeqOnce is an innovative, DeepTech company with expertise in qPCR, NGS, and novel tech development


The Genomics Market

SeqOnce was founded with a bold vision: to revolutionize Next Generation Sequencing (NGS) by making its sample preparation processes more efficient and straightforward.

Pivoting early in the Pandemic, the company developed and sold qPCR reagents for COVID tests.

Today, SeqOnce boasts a broad multi technology product portfolio designed to sustain revenue and lower barriers to market entry.  

A solid company built upon existing commercial and operations infrastructure

  1. Proven experience to manage significant revenue & subsequent opportunities
  2. Established customers & distributors
  3. Established supply chain, and proven R&D and Clinical Teams for new assay opportunities
  4. New opportunistic commercialization strategies

Product


SeqOnce has three technology platforms/franchises 
- qPCR, NGS, & NICER



qPCR: Our revenue workhorse
qPCR assays for respiratory pathogens, women’s health, and pathogen screening


Quantitative PCR (qPCR), also known as real-time PCR, is a method that amplifies and quantifies a target DNA sequence simultaneously.


Next Generation Sequencing (NGS)
 RhinoSeq, A fast library prep with patent protection


NGS is a modern DNA sequencing technology that enables the rapid sequencing of large amounts of DNA. We developed a technology to prepare the DNA sample faster than other methods.


NICER (New Technology)
A new molecular biology platform to disrupt the qPCR market



Traction


Forecast

Completed Milestones

  • Generated over $45m, with less than $1m invested
  • Current revenue run rate: $100-$250k+ per month
  • Invested COVID profit in R&D / new commercial lines
  • Launched two new novel technologies

Business model


SeqOnce develops, manufactures, and sells genomic tools, such as PCR assays, and next generation sequencing (NGS) libraries, into large international and existing markets consisting of clinical service labs, other biotech companies, pharmaceuticals, government labs, and academic institutions. This growing revenue helps fund the R&D for both an expanding product portfolio along with the advanced research to develop the next generation of game changing technologies.

Why Do Labs Use SeqOnce Products?

  • The lab business is very sticky.  Once a lab has validated a test with our reagents, the barrier to switch is costly and burdensome.
  • Our assays have been optimized, well validated, and utilize established supply chains based in the USA.
  • Clinical labs operate on high volume and low margin. They come to us to gain margin, and leverage off our innovative assay development team.

Customer Example


Recurring & Seasonal Revenue Growth

Vision and strategy


Now, building upon its deep roots in novel technology R&D, SeqOnce has developed NICER

2025 Investment Milestones / Use of Proceeds

Increase enterprise value prior to Series A priced round

  • Grow Revenue
  • Position company for growth
    • Establish internal manufacturing of key components, significantly expanding margins
    • Build commercial infrastructure to ramp qPCR and NGS sales
    • Commercial development opportunities for NICER
  • R&D of new qPCR assays, NGS assays, and NICER
  • Position company for Series A round / IPO


Leadership


A strong management team with experience in BioTech

The SeqOnce team has deep expertise in genomics and molecular biology including members from Roche, Sequenom, and Agilent


Deal terms


Valuation cap

$25,000,000

The maximum valuation at which your investment converts into equity shares or cash.
Learn more

Discount

20%

If a trigger event for SeqOnce Biosciences occurs, the discount provision gives investors equity shares (or equal value in cash) at a reduced price.
Learn more.

Minimum investment

$100

The smallest investment amount that SeqOnce Biosciences is accepting.
Learn more

Maximum investment

$500,000

The largest investment amount that SeqOnce Biosciences is accepting.
Learn more

Funding goal

$1.24M

The maximum amount the offering can raise is $1.24M.
Learn more

Deadline
SeqOnce Biosciences needs to reach their minimum funding goal before the deadline ( ). If they don’t, all investments will be refunded.
Learn more
Type of security

SAFE

A SAFE allows an investor to make a cash investment in a company, with rights to receive certain company stock at a later date, in connection with a specific event. · Learn more

How it works

Documents

Republic (OpenDeal Portal LLC, CRD #283874) is hosting this Reg CF securities offering by SeqOnce Biosciences Inc. View the official SEC filing and all updates:
Official SEC Logo Form C SEC.gov
Company documents
SeqOnce Biosciences SAFE SeqOnce - Form C .pdf

Bonus perks

In addition to your SAFE, you'll receive perks for investing in SeqOnce Biosciences.
Invest
$1,000
Receive
  • Pack of SeqOnce Stickers, including one of the Rhino
Invest
$2,500
Receive
  • An exclusive investors-only coffee mug, with the pic of the Rhino,
  • plus all tiers above
Invest
$7,500
Receive
  • Name on the Investor Surfboard that is the lobby at the company HQ,
  • plus all tiers above.
Invest
$15,000
Receive
  • A virtual call and tour of our HQ, with member of Sr. Staff
  • plus all tiers above

About SeqOnce Biosciences

Legal Name
SeqOnce Biosciences Inc
Founded
Feb 2014
Form
Delaware Corporation
Employees
11
Website
seqonce.com
Social Media
Headquarters
Google Map location of of SeqOnce Biosciences
1926 Kellogg Avenue 100 , Carlsbad, CA
Headquarters
1926 Kellogg Avenue, 100, Carlsbad, CA, United States 92008

SeqOnce Biosciences Team
Everyone helping build SeqOnce Biosciences, not limited to employees

Profile picture of Chris Angermayer, MBA
Chris Angermayer, MBA
CEO - Founder
Chris is a former finance industry executive turned genomics entrepreneur, and founder, with over 20 years of experience in leadership roles.
Profile picture of Joseph Dunham, PhD
Joseph Dunham, PhD
CSO - Founder
Joseph is an expert in molecular biology and genomics and is an inventor that holds multiple biotechnology patents. He is a founder, and develops and leads the scientific initiatives.
Profile picture of Tim Harkins, PhD
Tim Harkins, PhD
COO
Tim is an industry expert in diagnostics and genomics with 25 years in biotech. Parabricks (exit), Life Tech, Roche, Swift (exit) Amersham, NVIDIA, and Applied Biosystems.
Profile picture of Alan Horsager, PhD
Alan Horsager, PhD
CBO - Consulting
Alan is an biotech entrepreneur leading companies from early discovery to commercialization and acquisition. He recently founded Concept Bio, a venture studio dedicated to nurturing early-stage biotech companies.
Profile picture of Cyrus Arman, PhD, MBA
Cyrus Arman, PhD, MBA
Sr Strategist - Consulting
Cyrus is a Biotech entrepreneur. He recently founded Concept Bio, a venture studio dedicated to nurturing early-stage biotech companies.
Profile picture of Martin Pieprzyk
Martin Pieprzyk
Sr Commercial Advisor
Profile picture of Scott Fraser, PhD
Scott Fraser, PhD
Scientific Advisor
Profile picture of Scott Tighe
Scott Tighe
Scientific Advisor
5 more team members
Chris Angermayer, MBA
CEO - Founder
Joseph Dunham, PhD
CSO - Founder
Tim Harkins, PhD
COO
Alan Horsager, PhD
CBO - Consulting
Cyrus Arman, PhD, MBA
Sr Strategist - Consulting
Martin Pieprzyk
Sr Commercial Advisor
Scott Fraser, PhD
Scientific Advisor
Scott Tighe
Scientific Advisor
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SeqOnce Biosciences

SeqOnce Biosciences successfully raised $117,316 from 67 investors on May 1, 2025
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